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Experiment

Analytical Study on Cytokines in Pubertal and Adult Female C57BL/6 Mice Treated
with LPS
Summary Data Summary
Investigator Blaustein, Jeffrey
Description Applicable research area(s): Neurobiology
Status Completed
Public Release 6/20/2018
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagSame StrainExperiment Description
Data Analysis
TypeCount
Animals32
Experimental Conditions3
Catalog Items1
Curation Info (# flags)2
Phenotype Assays5
Phenotype Measurements160
Histology Images0
Publications0
Phenotypes6


Animals

Strain NameCommon NameFemalesMalesUnknown
C57BL/6
32
0
0


Experimental Factors
 Name / AbbreviationDescription

Experimental Factor: Drug Administered

 LPS
Lipopolysaccharide - induces bacterial infection
 Saline
Saline

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Time Since Drug Administered (hr)

 Time Since Drug Admi
The time, in hours, since the drug was administered to the subject.



No documents found.


Mammalian Phenotype (MP) Terms

MPTermIDMPTermNameDefinitionOther Results
MP:0008593increased circulating interleukin-10 level
increase in the amount in the blood of a cytokine produced by a variety of cell types| including T-cells| monocytes| dendritic cells and epithelial cells that exerts a variety of effects on immunoregulation and inflammation [MESH:D12.644.276.374.465.510]
MMPC Search Results
MP:0008596increased circulating interleukin-6 level
increase in the amount in the blood of a cytokine that stimulates the growth and differentiation of B-cells and is also a growth factor for hybridomas and plasmacytomas| and is produced by many different cells including T-cells| monocytes and fibroblasts [MESH:D12.644.276.374.465.506]
MMPC Search Results
MP:0008641increased circulating interleukin-1 beta level
increased in the amount in the blood of an interleukin-1 subtype that is synthesized as an inactive membrane-bound pro-protein on monocytes| macrophages and other cells; proteolytic processing of the precursor form by caspase 1 results in release of the active form of interleukin-1beta from the membrane [MESH:D12.644.276.374.465.501.600]
MMPC Search Results
MP:0008657increased interleukin-1 beta secretion
increase in the production or release of an interleukin-1 subtype that is synthesized as an inactive membrane-bound pro-protein on monocytes| macrophages and other cells; proteolytic processing of the precursor form by caspase 1 results in release of the active form of interleukin-1beta from the membrane [MESH:D12.644.276.374.465.501.600]
MMPC Search Results
MP:0008660increased interleukin-10 secretion
increase in the production or release of a cytokine produced by a variety of cell types| including T-cells| monocytes| dendritic cells and epithelial cells that exerts a variety of effects on immunoregulation and inflammation [MESH:D12.644.276.374.465.510]
MMPC Search Results
MP:0008705increased interleukin-6 secretion
increase in the production or release of a cytokine that stimulates the growth and differentiation of B-cells and is also a growth factor for hybridomas and plasmacytomas| and is produced by many different cells including T-cells| monocytes and fibroblasts [MESH:D12.644.276.374.465.506]
MMPC Search Results

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