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Experiment

Analytical Study to Measure Cytokines in NOD-Scid Mice Bearing shRNA-Mediated
Beclin1 or ATG5 Knockdown Tumor
Summary Data Summary
Investigator Shaw, Leslie
Description Breast tumors with low Beclin 1 expression are more aggressive. The mouse model
mimics low Beclin 1 expression in mammary tumors to investigate the mechanism by
which Beclin 1 impacts tumor behavior.

Applicable research area(s): Metabolism, Oncology
Status Completed
Public Release 11/2/2019
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagSame StrainMetadataNeed Conditions
Data Analysis
TypeCount
Animals19
Experimental Conditions2
Catalog Items1
Curation Info (# flags)3
Phenotype Assays29
Phenotype Measurements551
Histology Images0
Publications0


Animals

Strain NameCommon NameFemalesMalesUnknown
NOD.CB17-Prkdcscid/J
19
0
0


Experimental Factors
 Name / AbbreviationDescription

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Tumor

 GFP
 shRNA-ATG5 knockdown
 shRNA-Beclin1 knockdown



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