Metabolic Core
| Center | Case Western Reserve University |
|---|---|
| Website | http://www.case.edu/med/mmpc/Metabolic_Core.html |
| Description | The Metabolic Core conducts in vivo and ex vivo metabolic experiments on mice shipped to the Case MMPC. This core focuses on the following techniques and measurements: 1) Chronic or acute arterial, jugular and/or gastric catheterization 2) Acute catheterization of portal vein or urinary bladder 3) Energy expenditure integrated over four days by the "doubly-labeled water" method 4) Rates of fatty acid, cholesterol, triglycerides, or protein synthesis measured using 2H2O 5) Insulin clamp, pancreatic clamp 6) Food intake 7) Body temperature 8) Urine and blood chemistry analysis 9) Glycosylated hemoglobin 10) Liver perfusion and heart perfusion 11) Tissue perfusion and fixation |
