mmpc-logo mmpc-logo
twitter-logo    bluesky-logo
| Create Account | login
MICROMouse Program Application Abstract
Peritoneal microdialysis as an alternative to blood sampling in mice
Juan Marini   (Houston, TX)
The mouse has become the model of choice for the study of metabolic diseases due to the increasing availability of genetic models. However, the small size of this animal and the limited amount of blood that can be collected present challenges and prevent the full use of the multiple genotypes generated. Frequently, a single terminal blood sample is collected because the quantity required, or the method of collection, prevents the continuation of the experiment. Even if animals can be reused, a period of time is needed for the animals to recover. Although an arterial catheter can circumvent some of these problems, patency of the catheter and the amount of blood collected remain an issue. In this application we propose a novel method of sampling metabolites from peritoneal fluid for metabolic studies. The implantation of a chronic peritoneal cannula will offer easy access to the peritoneal cavity and will allow for multiple sampling events while minimally affecting the system studied.

Menu

Home
Contact
About MMPC
Animal Husbandry
Tests Data
Search Data
Analysis
Clients
MMPC Centers

Newsletter

Interested in receiving MMPC News?
twitter-logo Mouse Phenotyping
@NationalMMPC



2017 National MMPC. All Rights Reserved.