Isotope Tracers in Metabolic Research
| Announcing an NIH/MMPC sponsored course: |
5th Annual Course on
Isotope Tracers in Metabolic Research:
Principles and Practice of Kinetic Analysis
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March 12-16, 2012
The Peabody Little Rock
Little Rock, Arkansas
Course Directors: Robert Wolfe, PhD and Henri Brunengraber*, MD, PhD
Sponsored by NIDDK and organized on behalf of the NIH-sponsored Mouse Metabolic Phenotyping
Centers (MMPC)
This is the fifth annual offering of a course that provides basic introductory and
comprehensive information on performing metabolic studies using tracers labeled with
radioactive or stable isotopes, in man and in animals. The course is designed for
beginners as well as those with experience who wish to expand their capabilities
to more sophisticated problems. The faculty is well-versed in a variety of applications
and methodologies. The number of attendees is limited to 100.
Techniques will be presented for investigating whole body metabolism, for metabolite
balance across organs, intracellular flux rates and pathway regulation. General aspects
of modeling will be considered, as well as specific applications in the study of
carbohydrate, fat, protein metabolism and energy balance. Theoretical and practical
matters related to sample analysis by mass spectrometry and NMR will be discussed,
including detailed numerical examples of calculations involved in determining isotopic
enrichment and basic kinetic parameters. Advanced lectures will discuss in more detail
the use of positional and mass isotopomer analysis for intracellular flux rates and
various aspects of protein and amino acid metabolism. Applications in humans and
animal models (particularly mouse) will be considered.
Course material will be presented in organized lectures and informal workshops.
Problem sets and discussion questions will highlight each lecture. Lecture notes and problem sets
will be available to registrants to be downloaded from the web at the course. In addition to organized
sessions, attendees will have ample opportunities for personal interaction with faculty members to
discuss issues of particular interest to them in depth.
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*supported by R25 DK082376 to H. Brunengraber
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Director & Faculty Information
| Faculty: |
| Henri Brunengraber -- Course Co-Director |
| Shawn C. Burgess |
| Gary Cline |
| Nicolaas E. Deutz |
| Joanne Kelleher |
| Craig Malloy |
| Owen McGuinness |
| Bettina Mittendorfer |
| Stephen Previs |
| Michelle Puchowicz |
| Robert Wolfe -- Course Director |
Sponsored by:
Grant R25-DK082376 from NIDDK to H. Brunengraber
Mouse Metabolic Phenotyping Centers
University of Arkansas for Medical Sciences Donald W. Reynolds Institute on Aging
The National Institute of Diabetes & Digestive & Kidney Diseases
The National Heart, Lung & Blood Institute
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Registration & Accomodations
Registration and Payment must be received prior to March 1, 2012
Registration Fee:
Breakfast, lunch, 1 dinner, and course materials are included in the registration fee. Limited to 100 participants.
| Students / Post docs | $400 |
| Academic / Government scientists | $750 |
| Industry scientists | $1250 |
Accomodations
1-800-Peabody (1-800-732-2639)
Little Rock
Discounted rate: $145/night
Reservations Identifier: 5th Annual Isotope Tracers Conference
Registration Form:
Click here to download the Registration Form.
PAYMENT BY CREDIT CARD IS NOT AVAILABLE
Please send registration form with your check to:
Isotope Tracers Course
Deb Viane, Assistant
4301 W. Markham Street, Slot 806
Little Rock, AR 72205-7199
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Contact Information
Deborah Viane, Course Assistant
4301 W. Markham St., Slot 806
Little Rock, AR 72205-7199
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