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Strain
STOCK Tgfb1tm2.1Doe/J

Summary Data Summary
Official Name STOCK Tgfb1tm2.1Doe/J
Common Name STOCK Tgfb1tm2.1Doe/J
Description A floxed neomycin cassette was placed upstream of exon 6
with an additional loxP site placed downstream of exon 6.
The neomycin cassette was subsequently removed by transient
expression of cre recombinase leaving exon 6 floxed.
Germline transmission of the allele was confirmed by genomic
PCR.

Mice homozygous for this Tgfb1flox-ex 6 conditional allele
are viable and fertile, with loxP sites flanking exon 6 of
the Tgfb1 (transforming growth factor, beta 1) gene. When
bred to mice that express Cre recombinase, the resulting
offspring will have the floxed region deleted in the
cre-expressing tissues while leaving the precursor
pro-region and neighboring B9d2 (LOC232987) gene intact.
Development Status Phenotyping ongoing
Creation Method knockin
TypeCount
Investigators 1
Genomics - Modifications 1
Experiments 1


Investigators
NameInstitution
Pei-Yu ChenYale University


Genomic Information
GeneAllele 1Allele 2Protocol
Tgfb1knockin (lox)knockin (lox)Not Specified


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