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Strain
C57BL/6-Hsd17b13tm1Lex /Mmucd

Summary Data Summary
Official Name C57BL/6-Hsd17b13tm1Lex /Mmucd
Common Name C57BL/6-Hsd17b13tm1Lex /Mmucd
Description Coding exons 1 and 2 were targeted.
Targeted or gene trap mutations are generated in strain
129/SvEvBrd-derived embryonic stem (ES) cells. The chimeric
mice are bred to C57BL/6-Tyrc-Brd albino mice albino mice to
generate F1 heterozygous animals. These progeny are
intercrossed to generate F2 wild type, heterozygous, and
homozygous mutant progeny. On rare occasions, for example
when very few F1 mice are obtained from the chimera, F1
heterozygous mice are crossed to 129/SvEvBrd x C57BL/6
hybrid mice to yield additional heterozygous animals for the
intercross to generate the F2 mice.
Development Status Phenotyping ongoing
Creation Method knockout
TypeCount
Investigators 1
Genomics - Modifications 1
Experiments 1


Investigators
NameInstitution
Yaron RotmanNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)


Genomic Information
GeneAllele 1Allele 2Protocol
Hsd17b13knockoutknockoutNot Specified


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