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Catalog Item
Hypoglycemic clamp

CenterVanderbilt University School of Medicine
Center CoreMetabolic Regulation Core
Test No.V4050
Test PriceInquire for Pricing
DescriptionThe counter-regulatory response to hypoglycemia is assessed using the
hypoglycemic clamp. Hypoglycemic clamps are performed on conscious mice with
catheters chronically implanted in the jugular vein and carotid artery. Our
clamps include glucagon, catecholamines and corticosterone measures over time. A
defined hypoglycemic stimulus is created using an insulin infusion and a
variable glucose infusion to lower the glucose level to ~50-70 mg/dL for 120
min. The rate of fall is controlled across animals.
DataData will be collected for this catalog item
Keywordshyperglycemic clamp
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