mmpc-logo mmpc-logo
twitter-logo    bluesky-logo
| Create Account | login
Center Core
Animal Core

Center University of California Davis
Description The Animal Core provides extensive scientific support services, including
importation/exportation, colony management, customized mouse models,
rederivation and creation of genetically-modified mutant mice (e.g. CRISPR), and
re-animation of a variety of models (e.g., KOMP) cryopreserved and available
from the Mutant Mouse Resource and Research Center (MMRRC) Consortium. The Core
can also produce male and female cohorts of mice for in vivo phenotyping under a
variety of vivarium environments, including Specific Pathogen Free (SPF),
Gnotobiotic, and ABSL3 conditions. The Core operates a Microsurgery Suite, with
two expert microsurgeons, for development of surgically-manipulated mouse
models, such as bariatric surgical models, e.g. Vertical Sleeve Gastrectomy
(VSG) and Roux en Y Gastric Bypass (RYGB), as well as cannulation telemetry and
osmotic pump implants, in addition to providing microsurgery training services
for investigators and clinicians. In addition to testing, manipulation, and
sampling, investigator can have these surgically-manipulated models as well as
any genetically-engineered mouse lines shipped from our approved vendor barrier
vivarium directly into the recipient institution’s vivarium. The Core provides
ancillary services and procedures, including gut microbiome studies, blood and
tissue sampling, glucose and insulin tolerance tests, and more. The Core also
provides anatomic and clinical pathology services, including gross necropsy with
histology, clinical chemistry, and hematology. Testing can be customized to
include specific organ histologic examination, grading and photo documentation.
The Core is led by Kristin Grimsrud DVM, PhD, who oversees the mouse management
technicians. Denise M. Imai-Leonard, DVM, PhD, DACVP, and Director of the UC
Davis Comparative Pathology Laboratory, provides Core users with comprehensive
pathology services.
Center Core RRID SCR_015356 (Link)
Is Subcore? No
Is Inactive? No


 Members
NameInstitutionEmailTitle
Kristin GrimsrudUniversity of California Daviskngrimsrud@ucdavis.eduDirector

Menu

Home
Contact
About MMPC
Animal Husbandry
Tests Data
Search Data
Analysis
Clients
MMPC Centers

Newsletter

Interested in receiving MMPC News?
twitter-logo Mouse Phenotyping
@NationalMMPC



2017 National MMPC. All Rights Reserved.