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Experiment

NEFA, Leptin, Insulin, Adiponectin levels of PGT KO mice on C57/SV129 Mix
genetic background; MVSAECM0316
Summary Data Summary
Investigator Schuster, Victor
Description This mice is the prostaglandin transporter (PGT) knock-out mice. PGT is
responsible for prostaglandin turn-over in mammals. The PGT-KO mice have ~2x
increase in systemic prostaglandins. We are studying the effect of
prostaglandins on adipocyte biology.

The PGT KO mice have ~1/3 the body fat compared to the WT floxed controls, while
having double the food intake.

Applicable research area(s): Cardiovascular, Metabolism
Status Completed
Public Release 3/23/2018
Animal Age Measured In: month(s) post-natal (m)
Data Analysis
TypeCount
Animals36
Experimental Conditions2
Catalog Items4
Curation Info (# flags)0
Phenotype Assays4
Phenotype Measurements137
Histology Images0
Publications0
Phenotypes1


Animals

Strain NameCommon NameFemalesMalesUnknown
C57BLKS-PGT-/-
3
13
0
C57BLKS-PGT-/- Tg(EIIa-cre)C5379Lmgd
6
14
0

Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Mouse Diet

 Research Diets - D12451
Research Diets - D12451 Rodent Diet with 45% kcal% fat
Experimental Factor (Units)
Experimental Group
Mouse Diet



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