mmpc-logo mmpc-logo
twitter-logo    bluesky-logo
| Create Account | login
Publication
Glucose tolerance tests for systematic screening of glucose homeostasis in mice.
Authors Rozman J, Rathkolb B, Neschen S, Fuchs H, Gailus-Durner V, Klingenspor M, Wolf
E, Hrabe de Angelis M
Submitted By Submitted Externally on 7/24/2015
Status Published
Journal Current protocols in mouse biology
Year 2015
Date Published
Volume : Pages 5 : 65 - 84
PubMed Reference 25727201
Abstract This article presents a detailed description of intraperitoneal and oral glucose
tolerance tests in mice. The former is widely used in initial high-throughput
phenotyping of mutant mice to assess a diabetic phenotype and alterations in
glucose homeostasis. Each protocol provides a comprehensive description of each
step in the workflow, including variation of the standard protocol under
particular circumstances (e.g., sensitivity to food deprivation, excessive
deviations in body composition, or need for extra blood samples for additional
analyses). We also describe how reduction of body mass and body temperature can
be used as additional readouts to monitor metabolic function in response to food
deprivation.




Menu

Home
Contact
About MMPC
Animal Husbandry
Tests Data
Search Data
Analysis
Clients
MMPC Centers

Newsletter

Interested in receiving MMPC News?
twitter-logo Mouse Phenotyping
@NationalMMPC



2017 National MMPC. All Rights Reserved.