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Publication
Copolymer-Mediated Cell Aggregation Promotes a Proangiogenic Stem Cell Phenotype
In Vitro and In Vivo.
Authors Crowder SW, Balikov DA, Boire TC, McCormack D, Lee JB, Gupta MK, Skala MC, Sung
HJ
Submitted By Submitted Externally on 12/21/2016
Status Published
Journal Advanced healthcare materials
Year 2016
Date Published 11/1/2016
Volume : Pages 5 : 2866 - 2871
PubMed Reference 27717208
Abstract Material-induced cell aggregation drives a proangiogenic expression profile.
Copolymer substrates containing cell-repellent and cell-adhesive domains force
the aggregation of human mesenchymal stem cells, which results in enhanced
tubulogenesis in vitro and stabilization of vasculature in vivo. These findings
can be used to design instructive biomaterial scaffolds for clinical use.




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