mmpc-logo mmpc-logo
twitter-logo    bluesky-logo
| Create Account | login
Publication
Interactions between Intestinal Microbiota and Host Immune Response in
Inflammatory Bowel Disease.
Authors Zhang M, Sun K, Wu Y, Yang Y, Tso P, Wu Z
Submitted By Submitted Externally on 4/24/2018
Status Published
Journal Frontiers in immunology
Year 2017
Date Published
Volume : Pages 8 : 942
PubMed Reference 28855901
Abstract Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the
gastrointestinal tract. Although the etiology and pathogenesis of IBD remain
unclear, both genetic susceptibility and environmental factors are implicated in
the initiation and progression of IBD. Recent studies with experimental animal
models and clinical patients indicated that the intestinal microbiota is one of
the critical environmental factors that influence nutrient metabolism, immune
responses, and the health of the host in various intestinal diseases, including
ulcerative colitis and Crohn's disease. The objective of this review is to
highlight the crosstalk between gut microbiota and host immune response and the
contribution of this interaction to the pathogenesis of IBD. In addition,
potential therapeutic strategies targeting the intestinal micro-ecosystem in IBD
are discussed.




Menu

Home
Contact
About MMPC
Animal Husbandry
Tests Data
Search Data
Analysis
Clients
MMPC Centers

Newsletter

Interested in receiving MMPC News?
twitter-logo Mouse Phenotyping
@NationalMMPC



2017 National MMPC. All Rights Reserved.