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Publication
Single Quantum Dot Tracking Illuminates Neuroscience at the Nanoscale.
Authors Kovtun O, Tomlinson ID, Bailey DM, Thal LB, Ross EJ, Harris L, Frankland MP,
Ferguson RS, Glaser Z, Greer J, Rosenthal SJ
Submitted By Submitted Externally on 11/5/2018
Status Published
Journal Chemical physics letters
Year 2018
Date Published 8/1/2018
Volume : Pages 706 : 741 - 752
PubMed Reference 30270931
Abstract The use of nanometer-sized semiconductor crystals, known as quantum dots, allows
us to directly observe individual biomolecular transactions through a
fluorescence microscope. Here, we review the evolution of single quantum dot
tracking over the past two decades, highlight key biophysical discoveries
facilitated by quantum dots, briefly discuss biochemical and optical
implementation strategies for a single quantum dot tracking experiment, and
report recent accomplishments of our group at the interface of molecular
neuroscience and nanoscience.




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