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Strain
B6.Cg-Ppargtm2Rev Tg(Syn1-cre)671Jxm

Summary Data Summary
Official Name B6.Cg-Ppargtm2Rev Tg(Syn1-cre)671Jxm
Common Name B6.Cg-Ppargtm2Rev Tg(Syn1-cre)671Jxm
Description Pparg knockin: A single loxP site was introduced upstream of
exon 1 and a floxed neomycin cassette was inserted
downstream of exon 2. The neomycin gene was excised from
correctly targeted ES cells by transient transfection with a
Cre expression plasmid.

Tg(Syn1-cre): This transgene expresses Cre recombinase under
the control of a rat synapsin I promoter. Cre recombinase
activity is detected in neuronal cells, including brain,
spinal cord and DRGs, as early as E12.5, as well as in
neurons in adult.
Development Status Phenotyping ongoing
Creation Method knockout
Breeding Type intercross
TypeCount
Investigators 1
Genomics - Modifications 1
Genomics - Transgenes 1
Experiments 2


Investigators
NameInstitution
Karen RyanUniversity of California Davis


Genomic Information
GeneAllele 1Allele 2Protocol
Ppargknockin (lox)knockin (lox)Not Specified
EnhancerPromoterGeneCopies
Not SpecifiedSyn1CRENot Specified


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