mmpc-logo mmpc-logo
twitter-logo    bluesky-logo
| Create Account | login
Strain
B6.129S4-Soat1tm1Far

Summary Data Summary
Official Name B6.129S4-Soat1tm1Far
Common Name Acat1 KO
Description Insertion of a neomycin cassette into a 5' early exon (amino
acids 50-100). Reduced levels of a truncated mRNA transcript
were detected by Northern blot on RNA from preputial glands.
No protein was detected by immunoblot analysis in
homogenates from preputial glands, ovaries and adrenals.
Development Status Phenotyping ongoing
Creation Method knockout
TypeCount
Investigators 1
Genomics - Modifications 1
Publications 1


Investigators
NameInstitution
Ta-Yuan ChangDartmouth Medical School


Genomic Information
GeneAllele 1Allele 2Protocol
Soat1knockoutknockoutNot Specified




PublicationAltmetricsSubmitted ByPubMed IDStatus
Myeloid Acyl-CoA:Cholesterol Acyltransferase 1 Deficiency Reduces Lesion Macrophage Content and Suppresses Atherosclerosis Progression.
Huang LH, Melton EM, Li H, Sohn P, Rogers MA, Mulligan-Kehoe MJ, Fiering SN, Hickey WF, Chang CC, Chang TY
The Journal of biological chemistry, 2016 (291), 6232 - 44
Submitted Externally
26801614
Published

Menu

Home
Contact
About MMPC
Animal Husbandry
Tests Data
Search Data
Analysis
Clients
MMPC Centers

Newsletter

Interested in receiving MMPC News?
twitter-logo Mouse Phenotyping
@NationalMMPC



2017 National MMPC. All Rights Reserved.