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Strain
B6.129S6-Rictortm1Mgn Tg(Adipoq-cre)1Evdr

Summary Data Summary
Official Name B6.129S6-Rictortm1Mgn Tg(Adipoq-cre)1Evdr
Common Name Adiponectin-Rictor KO
Description Rictor tm1Mgn: Two FRT sites flank a partial exon 3 which is
linked to the lacZ reporter plus a floxed neomycin cassette.
A third loxP site flanks intact exon 3 of the gene. QRT-PCR
confirmed the absence of transcription. This allele is a
hypomorph.
Development Status Phenotyping ongoing
Creation Method transgenic
TypeCount
Investigators 1
Genomics - Modifications 1
Genomics - Transgenes 1
Publications 1


Investigators
NameInstitution
David GuertinUniversity of Massachusetts Medical School


Genomic Information
GeneAllele 1Allele 2Protocol
Rictorknockin (lox)knockin (lox)Not Specified
EnhancerPromoterGeneCopies
Not SpecifiedAdipoqCRENot Specified




PublicationAltmetricsSubmitted ByPubMed IDStatus
Adipose tissue mTORC2 regulates ChREBP-driven de novo lipogenesis and hepatic glucose metabolism.
Tang Y, Wallace M, Sanchez-Gurmaches J, Hsiao WY, Li H, Lee PL, Vernia S, Metallo CM, Guertin DA
Nature communications, 2016 (7), 11365
Submitted Externally
27098609
Published

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