mmpc-logo
twitter-logo @NationalMMPC
| Create Account | login
Experiment

Analytical Study on Vaginal Cytokines in H041 (Gonorrhea)-Infected Rag2 KO Mice
Summary Data Summary
Investigator Ram, Sanjay
Description H041 is a strain of gonorrhea that was infected in mice.
Premarin was treated to help them get infected with gonorrhea.
Status Completed
Public Release 4/23/2018
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagSame StrainExperiment Description
Data Analysis
TypeCount
Animals76
Experimental Conditions5
Catalog Items1
Curation Info (# flags)2
Phenotype Assays22
Phenotype Measurements1672
Histology Images0
Publications0
Phenotypes6


Animals

Strain NameCommon NameFemalesMalesUnknown
C57BL/6J +/+
39
0
0
RAG-2 KO
37
0
0


Experimental Factors
 Name / AbbreviationDescription

Experimental Factor: Bacteria Introduced

 H041
A high-level ceftriaxone-resistant strain of Neisseria gonorrhoeae, called H041, discovered in Japan.
 Vehicle
Injection of vehicle without bacteria. Negative control

Experimental Factor: Drug Administered

 Premarin
Premarin is the brand name for an estrogen medication that consists of conjugated estrogens.

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Time Since Drug Administered (day)

 Time Since Drug Admi
The time, in days, since the drug was given to the subject.

Experimental Factor: Tissue Source

 vagina
vagina



No documents found.


Mammalian Phenotype (MP) Terms

MPTermIDMPTermNameDefinitionOther Results
MP:0008594decreased circulating interleukin-10 level
reduction in the amount in the blood of a cytokine produced by a variety of cell types| including T-cells| monocytes| dendritic cells and epithelial cells that exerts a variety of effects on immunoregulation and inflammation [MESH:D12.644.276.374.465.510]
MMPC Search Results
MP:0008596increased circulating interleukin-6 level
increase in the amount in the blood of a cytokine that stimulates the growth and differentiation of B-cells and is also a growth factor for hybridomas and plasmacytomas| and is produced by many different cells including T-cells| monocytes and fibroblasts [MESH:D12.644.276.374.465.506]
MMPC Search Results
MP:0008599increased circulating interleukin-2 level
increase in the amount in the blood of a soluble substance elaborated by antigen- or mitogen-stimulated T-cells which induces DNA synthesis in naive lymphocytes [MESH:D12.644.276.374.465.502]
MMPC Search Results
MP:0008661decreased interleukin-10 secretion
reduction in the production or release of a cytokine produced by a variety of cell types| including T-cells| monocytes| dendritic cells and epithelial cells that exerts a variety of effects on immunoregulation and inflammation [MESH:D12.644.276.374.465.510]
MMPC Search Results
MP:0008687increased interleukin-2 secretion
increase in the production or release of a soluble substance elaborated by antigen- or mitogen-stimulated T-cells which induces DNA synthesis in naive lymphocytes [MESH:D12.644.276.374.465.502]
MMPC Search Results
MP:0008705increased interleukin-6 secretion
increase in the production or release of a cytokine that stimulates the growth and differentiation of B-cells and is also a growth factor for hybridomas and plasmacytomas| and is produced by many different cells including T-cells| monocytes and fibroblasts [MESH:D12.644.276.374.465.506]
MMPC Search Results

Menu

Home
Contact
About MMPC
Animal Husbandry
Tests Data
Search Data
Analysis
Clients
MMPC Centers

Newsletter

Interested in receiving MMPC News?
twitter-logo Mouse Phenotyping
@NationalMMPC



2017 National MMPC. All Rights Reserved.