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Experiment

Metabolic measurements in Lipa KO mice treated with niclosamide
Summary Data Summary
Investigator Shengkan, Jin
Description 3 week old female FVB/N mice were treated with normal diet(ND) or normal diet
plus 2000ppm NEN for 4 weeks. Plasma samples were collected in 16-hr fasted mice
with heparin-coated tube and stored in -80. Liver samples were collected in 5-hr
fasted mice and stored in -80.

Applicable research area(s): Metabolism
Status Completed
Public Release 6/13/2018
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagSame StrainExperiment Description
Data Analysis
TypeCount
Animals14
Experimental Conditions5
Catalog Items6
Curation Info (# flags)2
Phenotype Assays7
Phenotype Measurements98
Histology Images0
Publications0


Animals

Strain NameCommon NameFemalesMalesUnknown
FVB/N
3
0
0
lal -/-
11
0
0

Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Fast Duration (hr)

 fast duration
Length of time the animal was fasted

Experimental Factor: Feeding Group

 Fasted
Animals are deprived of food but not water.

Experimental Factor: Mouse Diet

 Research Diets - D10012M
Research Diets - AIN-93M Rodent Diet with 9.4% fat, 75.9% carbohydrate, 14.7% protein
 Research Diets - D10012M 2000 ppm NEN
Research Diets - AIN-93M Rodent Diet with 9.4% fat, 75.9% carbohydrate, 14.7% protein supplemented with 2000 ppm niclosamide ethanolamine (NEN)

Experimental Factor: Tissue Source

 plasma (lithium heparin)
plasma (lithium heparin)



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