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Phenotype Assay
aspartate aminotransferase (AST)
units per liter (U/L)

Name aspartate aminotransferase
Abbreviation AST
Is Categorical? False
Tissue(s) liver
Group(s) enzymes
Description Aspartate transaminase (AST) catalyzes the reversible transfer of an a-amino
group between aspartate and glutamate and, as such, is an important enzyme in
amino acid metabolism. AST is found in the liver, heart, skeletal muscle,
kidneys, brain, and red bl
Protocol Not Specified

Experiments

OrderInvestigatorExperimentStatusMeasurements
11003Valentina Medici
Circulating ALT and AST levels in tx-J KO mice
Completed173
22336Rashmi Kothary
Analytical Study in Transgenic Mice with Mutation in Survival Motor Neuron Gene
Completed240
22350Holly Ingraham
Circulating FFA, AST, and insulin levels in liver specific Esr1 KO mice
Completed42
22132Tony Kang
Navitor Drug Trial Study 22 - Comprehensive Study to Assess Metabolic Profiles, Insulin Sensitivity, and Drug Toxicity in C57BL/6J Mice
Completed1179
21826Adrian Moore
UCB Drug Trial Study 9 - Comprehensive Study to Assess Metabolic Profiles and Insulin Sensitivity and Analytical Profiles for Drug Toxicity
Completed1904
19659Maximilian Muenke
Analytical Study in Gli2 and Shh Heterozygous KO Mice
Completed1529
18564Maximilian Muenke
Analytical Study in Gli2 Heterozygous KO Mice
Completed300
18518Caleb Kallen
Analytical Study in Lyz-TTP KO Mice Fed Chow and After High-fat Diet
Completed210
22108Jin Shengkan
Circulating cytokine levels in B6 mice treated with NEN, metformin, and cholestyramine
Completed351
22019Robert Farese
Analytical Study on Liver Function in NFR-B-Vps54wt/Mmmh Mice - A Model of ALS
Completed50
20724Jin Shengkan
Metabolic measurements in Lipa KO mice treated with niclosamide
Completed98
21813Jin Shengkan
Metabolic measurements in ApoE KO mice treated with metformin and niclosamide
Completed225
21832Jin Shengkan
Metabolic measurements in ApoE KO mice treated with metformin and niclosamide pt2
Completed360
18456Guangping Gao
Analytical Study-Metabolites-Liver Function in siRNA-treated Mice
Completed1860
18586Jin Shengkan
Metabolic measurements in B6 mice fed high fat diet and treated with fruit extracts
Completed90
22338Jin Shengkan
Circulating insulin, lipid, ALT, and AST levels in B6 mice fed high fat diet and treated with niclosamide
Completed126
22277Hea Jin Park
Analytical Study in High-Fat Diet Fed C57BL/6J Mice
Completed140



Associated MP Terms
  • MP:0000203 - abnormal circulating aspartate transaminase level
  • MP:0005343 - increased circulating aspartate transaminase level
  • MP:0005632 - decreased circulating aspartate transaminase level

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