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Experiment

Circulating cytokine levels in B6 mice induced with trauma and treated with
flavopiradol
Summary Data Summary
Investigator Haudenschild, Dominik
Description Quantify serum markers of systemic inflammation upon severe trauma in a mouse
model. Mice treated with one dose of 2.5mg/kg flavopiridol 4 hours after
surgical femur fracture.
Status Completed
Public Release 2/2/2019
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagSame StrainAnimal CountExperiment Description
Data Analysis
TypeCount
Animals34
Experimental Conditions11
Catalog Items1
Curation Info (# flags)3
Phenotype Assays5
Phenotype Measurements170
Histology Images0
Publications0


Animals

Strain NameCommon NameFemalesMalesUnknown
C57BL/6J
0
34
0


Experimental Factors
 Name / AbbreviationDescription

Experimental Factor: Drug Administered

 Flavopiridol
Flavopiridol hydrochloride is a potent CDK (cyclin-dependent kinase), and a CDC25 phosphatase family inhibitor.
 No Drug/Treatment
No Drug or Treatment done on these samples
 Vehicle
Vehicle - Control

Experimental Factor: Drug Dose (AU)

 Drug Dose
A numerical value indicating the dose of a drug administered. The unit of measure is indicated in the Drug Dose Units categorical value that accompanies this experimental condition.

Experimental Factor: Drug Dose Units

 mg/kg once
milligrams per kilogram one dose

Experimental Factor: Drug Injection Time (hr)

 DIT
The time a drug was injected into the animal. Negative values indicate the time the sample was measured before a drug was injected. A positive value indicates the time the sample was measured after a drug was injected.

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Fast Duration (hr)

 fast duration
Length of time the animal was fasted

Experimental Factor: Feeding Group

 Fed
Animals are allowed to have food.

Experimental Factor: Mouse Diet

 LabDiet 5001
crude protein (23.0%), crude fat (4.5%), crude fiber (6.0%), Ash (< 8.0%), minerals (2.5%)

Experimental Factor: Surgical Procedure

 femur fracture
The femur is experimentally fractured.

Experimental Factor: Time Sample Taken (min)

 Time Sample Taken
Time in minutes since a sample was taken

Experimental Factor: Tissue Source

 serum
serum



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