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Experiment

Circulating corticosterone and IGF-1 levels in B6 mice treated with FGF-21
Summary Data Summary
Investigator Ryan, Karen
Description 36 mice were placed on a high fat diet for 5 weeks then administered 0.2mg/kg
ibroblast growth factor-21 daily for 10 days.

Observe metabolic response to high fat diet and drug administration

Applicable research area(s): Obesity, Metabolism
Status Completed
Public Release 2/2/2019
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagSame Strain
Data Analysis
TypeCount
Animals36
Experimental Conditions8
Catalog Items2
Curation Info (# flags)1
Phenotype Assays2
Phenotype Measurements72
Histology Images0
Publications0
Phenotypes2


Animals

Strain NameCommon NameFemalesMalesUnknown
C57BL/6J
18
18
0


Experimental Factors
 Name / AbbreviationDescription

Experimental Factor: Drug Administered

 FGF-21
Fibroblast growth factor 21 is a protein that in mammals is encoded by the FGF21 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family and specifically a member of the "endocrine" subfamily which includes...
 Saline
Saline

Experimental Factor: Drug Dose (AU)

 Drug Dose
A numerical value indicating the dose of a drug administered. The unit of measure is indicated in the Drug Dose Units categorical value that accompanies this experimental condition.

Experimental Factor: Drug Dose Units

 mg/kg/d
milligrams per kilograms per day

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Fast Duration (hr)

 fast duration
Length of time the animal was fasted

Experimental Factor: Feeding Group

 Fasted
Animals are deprived of food but not water.

Experimental Factor: Mouse Diet

 Research Diets - D12492
Rodent Diet with 34% Fat, 60% kcal from Fat

Experimental Factor: Tissue Source

 plasma (EDTA)
plasma (EDTA)


Phenotype Assays Add / Edit



No documents found.

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