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Strain
B6.129S7-Adipoqtm1Pesch/+ Ldlrtm1Her

Summary Data Summary
Official Name B6.129S7-Adipoqtm1Pesch/+ Ldlrtm1Her
Common Name C57BL/6J-Adipoq-/+ Ldlr-/-
Description Adipoq heterozygote with WT and deleted allele present.

Mice homozygous for the Ldlrtm1Her mutation have an elevated
serum cholesterol level of 200-400 mg/dl and they have very
high levels (>2,000 mg/dl) when fed a high fat diet. Normal
serum cholesterol in the mouse is 80-100 mg/dl.
Development Status Phenotyping ongoing
Creation Method knockout
Maternal Strain C57BL/6J-Adipoqtm1Sche
Paternal Strain B6.129S7-Ldlrtm1Her/J
Background C57BL/6
Breeding Type intercross
TypeCount
Investigators 1
Genomics - Modifications 2


Investigators
NameInstitution
Willa HsuehOhio State University-Main Campus


Genomic Information
GeneAllele 1Allele 2Protocol
AdipoqknockoutwildNot Specified
LdlrknockoutknockoutNot Specified

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