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Analytical Study in Acat1 KO Mice
A novel mouse model for obesity and metabolic syndrome research
The Acat1-M/-M mice are resistant to high fat diet induced obesity.
Applicable research area(s): Diabetes, Obesity, Cardiovascular, Metabolism
month(s) post-natal (m)
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Curation Info (# flags)
Name / Abbreviation
Experimental Factor: Experimental Group
This animal belongs to the control group for the experiment.
This animal belongs to experimental group that is homozygous for gene manipulations.
Experimental Factor: Mouse Diet
Prolab 5P75 and 5P76 Isopro 3000 are the irradiated forms of RMH 3000 (5P00). The product has been irradiated to virtually bacteria-free dietary control. Protien 22.5%, Fat 5.4% Cholesterol 195 ppm
Teklad - 93075
Harlan-Teklad TD.93075 Adjusted Calorie diet (Calories: 21% protein, 55% Fat, 24% Carbohydrate) A diet used to induce obesity. Approximate fatty acid profile (% total fat): 28% saturated, 30% trans, 28% monounsaturated (cis), 14% polyunsaturated...
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Monocyte chemotactic protein-1 (CCL2)
Macrophage inflammatory protein 2-alpha (CXCL2)
Tumor necrosis factor alpha
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Mammalian Phenotype (MP) Terms
decreased adiponectin level
reduced concentration of a protein hormone that regulates glucose homeostasis and metabolism of lipids; it is normally produced by adipose tissue [MGI:csmith]
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