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Strain
C57BL/6-Cpt2tm1Mwol Tg(Alb-Cre)21Mgn

Summary Data Summary
Official Name C57BL/6-Cpt2tm1Mwol Tg(Alb-Cre)21Mgn
Common Name C57BL/6-Cpt2tm1Mwol Tg(Alb-Cre)
Description The albumin promoter drives the Cre transgene and produces a
liver specific knockout of the Cpt2 gene (floxed) where LoxP
sequences were inserted into the introns flanking exon 4 of
the gene.
Development Status Phenotyping ongoing
Creation Method knockin
Background C57BL/6
Breeding Type intercross
Phenotype Description Mice are protected from High Fat Diet (HFD)-induced fasting
hyperglycemia.
TypeCount
Investigators 1
Genomics - Modifications 1
Genomics - Transgenes 1
Publications 1


Investigators
NameInstitution
Michael WolfgangJohns Hopkins University


Genomic Information
GeneAllele 1Allele 2Protocol
Cpt2knockin (lox)knockin (lox)Not Specified
EnhancerPromoterGeneCopies
Not SpecifiedAlbCRENot Specified




PublicationAltmetricsSubmitted ByPubMed IDStatus
Hepatic Fatty Acid Oxidation Restrains Systemic Catabolism during Starvation.
Lee J, Choi J, Scafidi S, Wolfgang MJ
Cell reports, 2016 (16), 201 - 212
Submitted Externally
27320917
Published

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