mmpc-logo mmpc-logo
twitter-logo    bluesky-logo
| Create Account | login
Catalog Item
Indirect calorimetry / energy expenditure in the Promethion
Common Name(s): Body Composition, CLAMS & food intake behavior-meal patterns, Energy balance—food intake, energy expenditure, physical activity, Exercise capacity with gas exchange, Food Intake Behavior- Meal Patterns, Food/Water Ingestion, Wheel running

CenterVanderbilt University School of Medicine
Center CoreBody Weight Regulation Core
Test No.V3012
Test Price$100 per mouse per 5-7 days run
DescriptionWhole body VO2 and VCO2 is measured continuously in conscious mice using a
Promethion system (Sable Systems Int). The system is sensitive enough to measure
small changes in VO2, VCO2 and RQ. They can be used to measure resting or
exercising (running wheels or treadmill) gas exchange and energy expenditure.
The Promethion is very advanced, allowing for measurement and control of food or
water intake. In the Promethion the animals are housed in regular home cages
with normal bedding. Activity is measured using beam breaks and converted to
pedestrian locomotion. Food and water intake are very accurately quantified. The
system integrates all of these data to monitor behaviors and patterns. Body
weight and composition is included and measured before and after the metabolic
cages.

All mice remain in the Promethion cages for 5 days with continuous data
collection, allowing for acclimation while also providing extensive data. Full
data is reported to the investigator in excel format.
DataData will be collected for this catalog item
KeywordsActivity, basal metabolic rate, body composition, carbon dioxide, CO2
production, energy expenditure, food intake, gas exchange, indirect calorimetry,
obesity, oxygen, oxygen consumption, respiratory quotient, water intake, wheel
running
Tissues



Catalog Groups



Phenotype Assays



Experimental Factors
NameUnitsDescriptionAbbreviationMin ValueMax ValueCategoricalBatchOptions
Mouse Diet 
This is the food/chow mice were fed during the experiment.
 --TrueFalse
View
Drug Administered 
The drug that was administered during the study.
 --TrueFalse
View
Drug Dosearbitrary units
A numerical value indicating the dose of a drug administered. The unit of measure is indicated in the Drug Dose Units categorical value that accompanies this experimental condition.
Drug Dose0-FalseFalse
View
Drug Dose Units 
The units used for the drug dose experimental factor
Drug Dose Units00TrueFalse
View



Protocols

Menu

Home
Contact
About MMPC
Animal Husbandry
Tests Data
Search Data
Analysis
Clients
MMPC Centers

Newsletter

Interested in receiving MMPC News?
twitter-logo Mouse Phenotyping
@NationalMMPC



2017 National MMPC. All Rights Reserved.